HFC-227ea is used in
fire suppression systems that protect data processing and telecommunication facilities, and in fire suppression of many flammable liquids and gases. HFC-227ea is categorized as a Clean Agent and is governed by
NFPA 2001 - Standard for Clean Agent Fire Extinguishing Systems. Effective fire suppression requires introducing a concentration of the HFC-227ea agent between 6.25% and 9% depending on the hazard being suppressed. Its
NOAEL for cardiac sensitization is 9%. The
United States Environmental Protection Agency allows concentration of 9% volume in occupied spaces without mandated egress time, or up to 10.5% for a limited time. Most fire suppression systems are designed to provide concentration of 6.25-9%. The HFC-227ea fire suppression agent was the first non-ozone-depleting replacement for
Halon 1301. In addition, HFC-227ea leaves no residue on valuable equipment after discharge. HFC-227ea contains no chlorine or bromine atoms, presenting no
ozone depletion effect. Its atmospheric lifetime is approximated between 31 and 42 years. It leaves no residue or oily deposits and can be removed by ventilation of the affected space. As an
aerosol propellant, HFC-227ea is used in pharmaceutical metered dose inhalers such as those used for dispensing
asthma medication. ==Safety==