The 1948 United States Senate election in Nebraska took place on November 2, 1948. Incumbent Republican Senator Kenneth S. Wherry, who served as the Senate Majority Whip, ran for re-election to a second term. Wherry was challenged by former Congressman Terry Carpenter, the Democratic nominee. Despite significant Democratic gains nationwide, Wherry won re-election by a wide margin, defeating Carpenter with 57% of the vote. Wherry overperformed Republican presidential candidate Thomas Dewey by 2.55%, who won the state with 54.15% in the presidential election.