The 1950–51 Honduran Amateur League was the fourth edition of the Honduran Amateur League. F.C. Motagua obtained its 2nd national title. The season ran from 9 September 1950 to 23 January 1951.
Regional champions
For the first time the department of Yoro included a team to participate for the national championship. Known results ==National championship round==
National championship round
Played in a single round-robin format in Tegucigalpa between the regional champions. Also known as the Cuadrangular. Known results ==Motagua's lineup==