The Miami Airlines C-46 was preparing for a non-scheduled non-stop passenger flight from Newark to Tampa. Of the aircraft's two engines, the right engine took longer to start up; people nearby saw smoke continuously coming from that engine. At around 3:00 PM EST, the flight taxied out to runway 28, and was cleared for takeoff at 3:03. Just after takeoff, however, Newark
ATC personnel saw a trail of white smoke coming from the right side of the aircraft. The tower controller, concerned about the danger of there being a fire, pressed the airport crash alarm button. A Miami Airlines captain observing the takeoff from the ground also saw the smoke, which he believed was due to an overheated right brake. He telephoned the control tower and warned for the aircraft to keep its
landing gear down or, if it had already been raised, to extend it. The tower relayed his warning to the flight crew of the C-46, who acknowledged and started the process of lowering the landing gear. The aircraft continued ahead in the direction it took off in for a distance of about , slowly gaining an altitude of approximately . All throughout, the smoke progressively worsened; by the time the aircraft had reached the four-mile point, black smoke and actual flames could be seen trailing from the underside of the right engine
nacelle. Shortly after the landing gear was lowered, a large burst of flames erupted from underneath the right nacelle. The aircraft banked left to an angle of about 10 degrees and continued onwards in this position for another , gradually losing altitude as it went. While flying over the nearby city of Elizabeth, the aircraft, at an estimated altitude of just , suddenly lurched into a 90-degree left bank from which no recovery was possible. Although Captain Lyons managed to keep the aircraft from hitting the streets, apartment buildings, and a railroad depot below, the aircraft's left wingtip eventually struck the gabled roof of a vacant house near its ridge. The now-out-of-control aircraft then crashed nose-first into a one-story brick storage building owned by the Elizabeth Water Company before finally coming to rest on the banks of the
Elizabeth River. The aircraft's load of fuel ignited immediately upon impact, engulfing both remains of the aircraft and the wrecked storage building in a raging inferno. Nearby firefighters quickly arrived on the scene and extinguished the fire after about 17 minutes. The aircraft's wreckage came to rest in a generally inverted position and partially submerged in shallow water. All 52 passengers and 4 crew aboard the aircraft died, while another person on the ground was seriously injured. ==Aftermath==