The 1960 Ole Miss Rebels football team represented the University of Mississippi during the 1960 college football season. In their fourteenth season under head coach Johnny Vaught, the Rebels compiled a 10–0–1 record and won their fourth Southeastern Conference (SEC) championship. Their only blemish was a 6–6 tie against LSU. Mississippi was the only major-conference team in the nation that finished the season undefeated on the field.