The 1964 USC Trojans football team represented the University of Southern California (USC) in the 1964 NCAA University Division football season. In their fifth year under head coach John McKay, the Trojans compiled a 7–3 record, finished in a tie with Oregon State for the Athletic Association of Western Universities championship, and outscored their opponents 207 to 130. The Trojans ended their season with an upset victory over undefeated and top-ranked Notre Dame.