The 1980 South African Grand Prix was a Formula One motor race held on 1 March 1980 at Kyalami in Gauteng, South Africa. It was the third round of the 1980 Formula One season. The race was the twenty-sixth South African Grand Prix and the fourteenth to be held at Kyalami. The race was held over 78 laps of the 4.104-kilometre circuit for a total race distance of 320 kilometres.