The 1995 Iowa State Cyclones football team represented Iowa State University as a member of the Big Eight Conference during the 1995 NCAA Division I-A football season. Led by first-year head coach Dan McCarney, the Cyclones compiled an overall record of 3–8 with a mark of 1–6 in conference play, tying for seventh place at the bottom of the Big 8 standings. Iowa State played home games at Cyclone Stadium in Ames, Iowa.