The 1999 FedEx Championship Series season was the twenty-first in the Championship Auto Racing Teams (CART) era of American open-wheel car racing. It consisted of 20 races, beginning in Homestead, Florida on March 21 and concluding in Fontana, California on October 31. The season was marred by the fatal accidents of Gonzalo Rodríguez during practice for the Laguna Seca round and Greg Moore at the final round, in addition to various injuries that took several drivers out of championship contention.