(2,2,3-Trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase is an enzyme with systematic name ( -2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetate:CoA ligase (AMP-forming). This enzyme catalyses the following chemical reaction[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetate + ATP + CoA AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA