2-haloacid dehalogenase (configuration-retaining) (EC 3.8.1.11, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL-2-haloacid dehalogenase, DL-DEXr) is an enzyme with systematic name (S)-2-haloacid dehalogenase (configuration-retaining). This enzyme catalyses the following chemical reaction(1) (S)-2-haloacid + H2O (S)-2-hydroxyacid + halide (2) (R)-2-haloacid + H2O (R)-2-hydroxyacid + halide