A total of 65 teams were selected to participate in the tournament. Of that total, 31 of the teams earned automatic bids by winning their
conference tournaments.
Penn earned an automatic bid by winning the regular-season title of the
Ivy League, which did not conduct a conference tournament. The remaining 34 teams were granted "at-large" bids, which are extended by the NCAA Selection Committee. The initial game on March 14 officially named the
opening round game, but popularly called the "play-in game", had
Monmouth, winner of the
Northeast Conference tournament, facing
Hampton, who won the
Mid-Eastern Athletic Conference tournament, for a chance to play top seed
Villanova in the first round of the Tournament. Monmouth defeated Hampton, 71–49, to advance to play Villanova. All teams were seeded from 1 to 16 within their regions. The
Selection Committee seeded the entire field from 1 to 65. In a practice used since
2004, the ranking of the four top seeds against each other would determine the pairings in the Final Four. The top overall seed would be seeded to play the fourth overall seed in the national semifinals, should both teams advance that far. In 2006, these rankings were as follows: No. 1
Duke, No. 2
Connecticut, No. 3
Villanova, and No. 4
Memphis. ==Schedule and venues==