The draft order was determined by the
2010 Major League Baseball season standings. The
Pittsburgh Pirates received the first pick after having the worst record in 2010. The
Arizona Diamondbacks,
San Diego Padres, and
Milwaukee Brewers each received a compensation pick for failing to sign draft picks from the 2010 draft. Also, teams lost draft picks for signing certain free agents, while teams losing free agents received draft picks as compensation. The
Elias Sports Bureau ranks all players based on performance over the past two seasons, with the top 20% being considered "Type A" and the next 20% considered "Type B".{{cite news On September 8, 2019,
Danny Hultzen became the last of the first 29 picks to appear in an MLB game, when he made his debut for the
Chicago Cubs.
First round selected
Gerrit Cole first overall. As of 2023, Cole is a 6×
All-Star and an
American League Cy Young Award winner.
Supplemental first round ==Compensation picks==