Two main favourites were named before the race, 2005 and 2006 winner
Tom Boonen and 2010 winner
Fabian Cancellara, with outsiders including
Matti Breschel,
Sylvain Chavanel,
Peter Sagan,
Filippo Pozzato and
Sep Vanmarcke. A group of 15 riders, including amongst others
Tyler Farrar,
Pablo Lastras and
Maarten Tjallingii, formed the early breakaway, but due to the size of the group there were not allowed to gain more than five minutes over the peloton. In the peloton, the first attacks came during the first ascent of the Oude Kwaremont after about , eliminating some of the lesser riders, but still leaving a big group chasing the leaders. But the first major event happened some later, as Cancellara crashed out of the race, fracturing his
collar bone in four places. At the start of the second ascent of the Paterberg, several riders crashed in the first part of the peloton, allowing a very select group of riders to take some advantage over the rest of the peloton. This elite group, which amongst others contained Boonen,
Niki Terpstra, Chavanel, Sagan, Vanmarcke, Pozzato,
Alessandro Ballan,
Luca Paolini and
Vincent Jérôme, raced past the remainder of the breakaway group and at that point seemed to be battling it out for the win. However, the riders stopped cooperating and in the peloton chased hard in an attempt to bring
Edvald Boasson Hagen back to the lead group, succeeding just before the third ascent of the Oude Kwaremont. During this ascent, Ballan raced away from the pack, only to be caught a few minutes later by Pozzato and Boonen. Ballan, Boonen and Pozzato climbed the final ascent of the Paterberg together and despite numerous attempts by Ballan to get away from the other two, the three riders contested the sprint for the victory. In Oudenaarde, Boonen outsprinted Pozzato by one bike-length at the line, with Ballan taking third place. In a group of 43 riders finishing within one minute of the three leaders,
Greg Van Avermaet finished in fourth place, edging out Sagan in fifth. were represented three times within the top ten; along with Boonen's win, Terpstra and Chavanel also placed highly. ==General standings==