In the knockout stages, the 16 teams played a
single-elimination tournament, with the following rules: • Each tie was played on a home-and-away
two-legged basis, with the higher-seeded team hosting the second leg. However, CONMEBOL required that the second leg of the finals must be played in South America, i.e., a finalist from Mexico must host the first leg regardless of seeding. • In the round of 16, quarterfinals, and semifinals, if tied on aggregate, the
away goals rule was used. If still tied, the
penalty shoot-out was used to determine the winner (no
extra time was played). • In the finals, if tied on aggregate, the
away goals rule was not used, and 30 minutes of
extra time was played. If still tied after extra time, the
penalty shoot-out was used to determine the winner. • If there were two semifinalists from the same association, they must play each other. ==Bracket==