The Blues started the season sluggish, and head coach
Mike Yeo was fired on November 19 with the team's record at 7–9–3.
Craig Berube, who had served as assistant coach with the Blues since 2017, was named the interim head coach. Soon after, rookie goaltender
Jordan Binnington joined the team. On January 7, he won his first game in a shutout and took over as the team's starting goaltender. The Blues then went on a franchise-record 11-game winning streak and had a 30–10–5 run to finish the season. They clinched a playoff spot on March 29, 2019. In the
playoffs, the Blues defeated the
Winnipeg Jets,
Dallas Stars, and
San Jose Sharks to advance to the
2019 Stanley Cup Finals, where they faced the
Boston Bruins. It was their first Finals appearance since
1970. On May 29, 2019, St. Louis won a Stanley Cup Finals game for the first time in franchise history as they defeated the Bruins 3–2 in overtime in Game 2; the team was swept in their three previous finals trips (
1968,
1969, and
1970). On June 12, 2019, they defeated the Bruins in seven games to win the first Stanley Cup title in franchise history. Until then, they were the oldest franchise to have never won a Stanley Cup.
Ryan O'Reilly, who had been acquired in a trade during the previous offseason, was the Blues' top regular season scorer with 77 points. He then had a franchise-record 23 playoff points and won the
Conn Smythe Trophy as the most valuable player in the playoffs. O'Reilly also won the
Frank J. Selke Trophy for the league's best defensive forward during the regular season. =="Gloria"==