UPDF,
Proline FC and Masavu FC Entebbe were relegated from the
2017–18 Uganda Premier League. They were replaced by
Nyamityobora FC, who won the Rwenzori group of the 2017–18 FUFA Big League,
Ndejje University, and
Paidha Black Angels, who won the promotion playoff. All three promoted teams would be relegated this season. Some of the Kampala clubs may on occasions also play home matches at the
Mandela National Stadium. ==League table==