The 2018 Trofeo Alfredo Binda-Comune di Cittiglio was the 43rd running of the Trofeo Alfredo Binda, a women's cycling race in Italy. It was the third event of the 2018 UCI Women's World Tour season and was held on 18 March 2017. The race started in Gavirate and finished in Cittiglio, on the outskirts of Lago Maggiore in Northwest Italy.