Schedule Note: Intra-division opponents are in
bold text.
Game summaries Week 1: at Cleveland Browns Though favored to lose, the Titans surprised the league with a blowout win over the heavily hyped Browns in Cleveland with a strong second-half performance. The Titans defense intercepted QB
Baker Mayfield three times, including once for a pick-six by CB
Malcolm Butler, and sacked Mayfield four times, including once for a safety by
Cameron Wake. Titans QB
Marcus Mariota and RB
Derrick Henry had efficient games, leading the team to four touchdowns on offense to complement the strong defensive performance.
Week 2: vs. Indianapolis Colts The Titans lost a close game 19–17, though a highlight of the game involved a passing touchdown from Mariota to offensive lineman
David Quessenberry, who had recovered from a bout with cancer.
Week 3: at Jacksonville Jaguars The Titans faced traditional rival Jacksonville in a Thursday night matchup for the fifth time in six years, but lost after an effective performance by Jaguars quarterback
Gardner Minshew. With their second straight loss, the Titans fell to 1–2.
Week 4: at Atlanta Falcons For the first time all season, Marcus Mariota was not sacked during a game, after being sacked a league-high 17 times in the first three games of the season. The Titans easily won 24–10 to improve to 2–2, despite Falcons QB
Matt Ryan throwing for nearly 400 yards.
Week 5: vs. Buffalo Bills In a defense-heavy game, the Titans fell short partly due to four missed field goals from kicker
Cairo Santos, who was released after this game. However, the offense was also held in check by a strong Bills defense, as Mariota was sacked five times despite offensive tackle
Taylor Lewan returning from suspension. With their third straight loss to Buffalo, Tennessee fell to 2–3 on the year.
Week 6: at Denver Broncos After an ineffective performance, Marcus Mariota was benched for backup quarterback
Ryan Tannehill in the third quarter as the Titans were shut out 16–0. With the loss, Tennessee fell to 2–4.
Week 7: vs. Los Angeles Chargers Ryan Tannehill made his first start at quarterback for the Titans in place of Marcus Mariota. After a back-and-forth first half, the Titans pulled ahead in the second half, holding a 23–13 fourth quarter lead before the Chargers scored a touchdown, cutting the Titans' lead to 3 with just over 5 minutes left. After forcing the Titans to turn the ball over on downs at the Los Angeles 49-yard line, the Chargers marched down the field to the Titans 1-yard line, but running backs
Austin Ekeler and
Melvin Gordon were unable to score, with the Titans defense forcing Gordon to fumble at the goal line. The Titans recovered the ball for a touchback, effectively sealing the win to improve to 3–4.
Week 8: vs. Tampa Bay Buccaneers The Titans rallied after the Buccaneers had themselves rallied from a 17–9 Tennessee lead.
Jameis Winston's two touchdowns and a two-point conversion throw put the Buccaneers up 23–17 halfway through the third quarter.
Cody Parkey's field goal put the Titans within 23–20 late in the third then
Ryan Tannehill led a drive ending in an
A. J. Brown touchdown catch that put Tennessee up 27–23. Winston fumbled on one Buccaneers possession, then was intercepted on Tampa's final possession.
Week 9: at Carolina Panthers Week 10: vs. Kansas City Chiefs The game lead tied or changed six times and the Titans rallied to the win on two field goal miscues by the Chiefs, first on a blown snap, subsequent missed throw by
Dustin Colquitt, and resulting intentional grounding penalty while Tennessee trailed 32–27, then following an
Adam Humphries touchdown catch and
Ryan Tannehill two-point conversion run, on a blocked
Harrison Butker 52-yard attempt, the kick blocked by
Joshua Kalu. It was the Titans’ eighth win in nine matchups to that point over teams coached by
Andy Reid.
Week 12: vs. Jacksonville Jaguars This game was notable because the four touchdowns scored by the Titans in the third quarter came in a span of six offensive plays.
Week 13: at Indianapolis Colts Week 14: at Oakland Raiders In a game with heavy playoff implications, the Titans scored three unanswered touchdowns in the second half after being locked in a 21–21 tie with the Raiders at halftime. Tennessee finished with 551 total yards as Ryan Tannehill passed for nearly 400 yards and Derrick Henry also posted a strong performance. With the win, the Titans improved to 8–5, reaching a tie with the
Pittsburgh Steelers for the sixth seed in the AFC.
Week 15: vs. Houston Texans Week 16: vs. New Orleans Saints Week 17: at Houston Texans With this win, the Titans clinched the #6 seed in the AFC. They also won their first game in Houston since
2011. RB
Derrick Henry achieved the most rushing yards in the league, surpassing Browns RB
Nick Chubb.
Standings Division Conference ==Postseason==