The league consisted of eighteen teams; fourteen teams remaining from the previous season, four teams promoted from the
Cypriot Third Division, and no teams were relegated from the
Cypriot First Division.
Teams promoted to 2020–21 Cypriot First Division •
Ermis Aradippou •
Karmiotissa Teams promoted from 2019–20 Cypriot Third Division •
Achyronas Liopetriou •
PAEEK •
Kouris Erimis •
THOI Lakatamia :
Note: Table lists clubs in alphabetical order. ==Season==