The 2020–21 Valparaiso University men's basketball team represented Valparaiso University during the 2020–21 NCAA Division I men's basketball season. Valpo, led by fifth-year head coach Matt Lottich, played their home games at the Athletics–Recreation Center as members of the Missouri Valley Conference. They finished the season 10–18, 7–11 in MVC play to finish a three-way tie for fifth place. As the No. 6 seed in the MVC tournament, they lost to Missouri State in the quarterfinals.