The tornado first touched down around 12:32 a.m. CST (06:32 UTC) in western
Davidson County along
SR 251, northeast of
Pegram. Initially, just trees were downed as the tornado crossed the
Cumberland River and moved through Bells Bend, where a barn was also destroyed. Damage along this initial segment of the path was rated EF0 to EF1. The tornado crossed the river a second time before heavily damaging the
John C. Tune Airport and an industrial area along Centennial Boulevard, including a terminal and the headquarters of
Western Express, Inc. at high-end EF2 strength. The airport sustained significant damage to its terminal and other buildings, with 17 metal hangars on the property destroyed. More than 90 aircraft parked at the airport, including charter jets, smaller airplanes, and a news helicopter operated by
CBS affiliate
WTVF were destroyed. Maintaining high-end EF2 strength, it crossed
SR 155 and struck the former
Tennessee State Prison, which sustained considerable structural damage. A communications tower and metal truss transmission towers were downed nearby. The tornado crossed the Cumberland River a third time and traveled through river bottomland in the
Bordeaux neighborhood, snapping trees, producing roof damage to a few homes and the Bordeaux nursing home, and destroying a few small sheds and outbuildings. It then crossed the river again and struck the northern part of the
Tennessee State University campus at EF2 intensity. Agricultural buildings on the campus were heavily damaged, resulting in the deaths of two calves and injuries to several goats. East of this location, the tornado produced EF1 to EF2 damage in the
North Nashville neighborhood, mainly to numerous homes and a few businesses. Some small homes sustained roof and exterior wall loss in this area, and many trees and power lines were downed. The tornado grew to nearly two-thirds of a mile () wide as it crossed
I-65 and moved into
Germantown, just north of the
Tennessee State Capitol, where it produced a widespread swath of mid to high-end EF2 damage. Throughout Germantown, numerous homes, churches, and apartment buildings sustained significant structural damage, including several large, multi-story apartment buildings that had their roofs and upper-floor exterior walls ripped off. An
O'Reilly Auto Parts store was damaged and an
AutoZone was almost completely destroyed. The Tennessee Department of Human Services building was largely destroyed, with its roof ripped off and some exterior walls collapsed. Around this time, local news media in Nashville began reporting
power flashes and showing numerous videos of the tornado as it moved through the area, including WTVF, whose studio facility—located along James Robertson Parkway between Germantown and the State Capitol—narrowly missed a direct hit by the tornado. This section of the track was similar to the path of the
F3 tornado that struck parts of Downtown Nashville on April 16, 1998, which also narrowly missed the WTVF building. After crossing the Cumberland River for the fifth time along the
Jefferson Street Bridge, the tornado struck
Topgolf and an industrial area, causing damage at EF1 to EF2 intensity. A
U-Haul store was destroyed, with numerous moving trucks flipped and tossed. Numerous businesses, restaurants, bars, homes, and apartment buildings were damaged or destroyed in Five Points, including Basement East, a popular music venue, which sustained major structural damage. A
YMCA was badly damaged, and a
Dollar General store was completely destroyed. Two fatalities occurred in Five Points when two pedestrians were struck by debris on McFerrin Avenue. where many homes were damaged in this residential area. Numerous houses sustained minor to moderate damage along this segment of the path, though a few homes were significantly damaged. The tornado then moved into
Donelson, crossing the
Stones River twice and destroying much of
Donelson Christian Academy and the Stanford Estates subdivision as it rapidly re-intensified. The tornado crossed
US 70 and then the Stones River a third time and continued into the southern part of
Hermitage at high-end EF2 intensity. Numerous homes and industrial buildings sustained severe damage in Hermitage, along with Dodson Chapel United Methodist Church, in the area of
SR 265,
SR 45, and Tulip Grove Road.
Kroger,
Panera Bread, and
Petco, in addition to multiple apartment buildings, sustained considerable damage along SR 45. The tornado maintained EF2 strength as it paralleled
I-40 into
Wilson County. producing a large swath of high-end EF3 damage as it crossed North Mount Juliet Road and substantially damaged Mount Juliet Christian Academy, West Wilson Middle School, and Stoner Creek Elementary. Numerous homes throughout town were heavily damaged or destroyed, a few of which were completely leveled. Two fatalities occurred in western Mount Juliet along Catalpa Drive. Maintaining EF3 intensity along a swath, the tornado continued east of Mount Juliet along the north side of I-40 towards
Lebanon, causing severe damage in residential, commercial, and industrial areas between the two cities. The last area of EF3-strength damage was observed to warehouses along Eastgate Boulevard before the tornado weakened to EF2 intensity, producing more damage across
SR 109 and along Leeville Pike and Tuckers Gap Road. Extensive tree damage occurred in this area, and multiple well-built homes had their roofs ripped off, a few of which had some exterior walls collapse. Two metal truss electrical transmission towers were blown over near Tuckers Gap Road before the tornado weakened to high-end EF1 strength and entered Lebanon. In Lebanon, many homes and businesses suffered considerable damage, including two large cemeteries,
Lebanon Municipal Airport,
Walmart, and
Lowe's, as the tornado crossed South Hartmann Drive, South Maple Street, and US 231. The Wilson County Fairgrounds was affected as the tornado crossed US 70 and moved east out of town. Frame homes were damaged, and some mobile homes and outbuildings were destroyed in this area. It continued along the interstate between Lebanon and
Tuckers Crossroads, causing damage on both sides of the interstate along Bluebird Road and Coe Lane. As the tornado passed Linwood Road, a gas station and a heavy equipment auctioneer's property sustained low-end EF2 damage. The gas station had a canopy blown over and a couple exterior walls knocked down. Continuing into
Smith County, the tornado produced EF1-type damage in the
Grant and
New Middleton communities, snapping and uprooting many trees, damaging or destroying barns and outbuildings, and causing considerable roof damage to homes. The tornado dipped south of the interstate at New Middleton, continuing to damage houses and destroy outbuildings as it crossed ridges and valleys through southern
Gordonsville, with most of the damage occurring on Agee Branch Road,
Hickman Highway, and Maple Street. A couple of mobile homes were damaged or destroyed in the Gordonsville area as well, including one that was flipped on top of a truck on Hickman Highway, and damage in this area was rated high-end EF1. More tree and structural damage was observed as the tornado left Gordonsville at EF1 intensity before it lifted east-northeast of
Hickman along
SR 141 at 1:35 a.m. CST (07:35 UTC). == Aftermath ==