The competition consists of one preliminary round, followed by ten proper rounds. All rounds were single-match elimination rounds, with the exception of the semi-finals which are again held over two legs. When tied after 90 minutes in the first three rounds, penalties were taken immediately. From round four, when tied after 90 minutes first an extra time period of 30 minutes was played, then penalties were taken if still necessary. Teams entered the competition in different rounds, based upon their
2021–22 league affiliation. Teams from the fifth-level
Belgian Division 3 or lower began in round 1, with the exception of six teams from the
Belgian Provincial Leagues which were randomly drawn to start in the preliminary round.
Belgian Division 2 teams entered in round 2,
Belgian National Division 1 teams entered in round 3,
Belgian First Division B teams in round 5 (except two already in round 3) and finally the
Belgian First Division A teams entered in round 6 (except two already in round 5). ==Round and draw dates==