2021–22 Iowa State Cyclones men's basketball team

In a season limited due to the ongoing COVID-19 pandemic, the Cyclones finished the 2020–21 season 2–22, 0–18 in Big 12 play to finish in last place. They lost to Oklahoma in the first round of the Big 12 Conference tournament. Following the winless conference season, the school fired head coach Steve Prohm after six years in Ames. On March 18, 2021, it was announced that the school had hired UNLV head coach and former Iowa State assistant Otzelberger as the team's new head coach. ==Offseason==

Departures Incoming transfers 2021 recruiting class ==Roster==

This is the second season that Big 12 Now on ESPN+ will air a number of Big 12 games. On May 20, 2021, Iowa State announced it would play in the 2021 NIT Season Tip-Off on November 24 and November 26. The tournament also featured Memphis, Virginia Tech, and Xavier. On June 2, the Big 12 announced matchups as part of the Big East-Big 12 Battle, with Iowa State traveling to Omaha, Nebraska to play Creighton and former Iowa State head coach Greg McDermott. The game will be played on December 4. Iowa will then travel to Ames as part of the Iowa Corn Cy-Hawk Series on December 9. On June 23, it was announced that the Cyclones will face Missouri in the Big 12/SEC Challenge. On June 30, Iowa State announced its nonconference schedule. {{CBB schedule end ==Rankings==

• AP does not release post-NCAA Tournament rankings.^Coaches do not release a Week 1 poll. ==References==