Market2021 MUSC Health Women's Open
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2021 MUSC Health Women's Open

The second 2021 Charleston Open was a tournament on the 2021 WTA Tour. It was played on outdoor green clay courts in Daniel Island. It was held one day after the 48th edition ended and was a replacement tournament for other tournaments that were not held because of travel restrictions, and organised by Charleston Tennis with a single-year licence in 2021, held at Family Circle Tennis Center from April 12 to 18, 2021.

Champions
Singles Astra Sharma def. Ons Jabeur, 2–6, 7–5, 6–1 DoublesHailey Baptiste / Caty McNally def. Ellen Perez / Storm Sanders, 6–7(4–7), 6–4, [10–6] == Singles main-draw entrants ==
Singles main-draw entrants
Seeds • 1 Rankings are as of April 5, 2021 Other entrants The following players received wildcards into the main draw: • Linda FruhvirtováEmma NavarroCoCo Vandeweghe The following player received entry as a special exempt: • Camila Osorio The following players received entry from the qualifying draw: • Claire LiuGrace MinAlycia ParksStorm Sanders Withdrawals ;Before the tournament • Amanda Anisimova → replaced by Caty McNallyIrina-Camelia Begu → replaced by Wang YafanAnna Blinkova → replaced by Liudmila SamsonovaDanielle Collins → replaced by Francesca Di LorenzoCoco Gauff → replaced by Viktoriya TomovaMadison Keys → replaced by Sara ErraniBarbora Krejčíková → replaced by Tereza MartincováAnn Li → replaced by Danka KovinićJessica Pegula → replaced by Clara TausonRebecca Peterson → replaced by Christina McHaleYulia Putintseva → replaced by Renata ZarazúaAnastasia Potapova → replaced by Stefanie VögeleLaura Siegemund → replaced by Kristie AhnSloane Stephens → replaced by Natalia Vikhlyantseva RetirementsAlizé CornetMisaki DoiTereza Martincová == Doubles main-draw entrants ==
Doubles main-draw entrants
Seeds • Rankings are as of April 5, 2021. Other entrants The following pair received a wildcard into the doubles main draw: • Sophie Chang / Emma Navarro The following pair received entry into the doubles main draw using a protected ranking: • Oksana Kalashnikova / Alla Kudryavtseva The following pair received entry into the doubles main draw as an alternate: • Linda Fruhvirtová / Tereza Martincová Withdrawals ;Before the tournament • Anna Blinkova / Lucie Hradecká → replaced by Elixane Lechemia / Ingrid NeelMisaki Doi / Nao Hibino → replaced by Linda Fruhvirtová / Tereza MartincováCoco Gauff / Caty McNally → replaced by Beatrice Gumulya / Jessy RompiesMakoto Ninomiya / Yang Zhaoxuan → replaced by Jamie Loeb / Erin Routliffe ;During the tournament • Linda Fruhvirtová / Tereza Martincová Retirements Arina Rodionova / Rosalie van der Hoek ==References==
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