On 2 March 2022,
Eritrea withdrew from the preliminary round. The first legs were played on 23 and 24 March, and the second legs were played on 27 and 29 March. In May, Mauritius were awarded a 3–0 win in their first leg against São Tomé and Príncipe, allowing them to reach the group stage with a 6–3 aggregate score, after the goalscorer for the latter
Luís Leal was found to have breached the COVID-19 regulations. However, in June, São Tomé and Príncipe had their appeal honoured and the result of the first leg was allowed to stand, enabling them to qualify for the next stage 4–3 on aggregate.
São Tomé and Príncipe won 4–3 on aggregate. ----
South Sudan won 5–2 on aggregate. ----
Lesotho won 3–1 on aggregate. ----
Eswatini won 5–1 on aggregate. ----
Gambia won 3–2 on aggregate. ==Goalscorers==