March–April May June On June 15,
Gio Urshela sustained an injury, later revealed to be a fractured pelvis and will be out for a significant amount of time. With both 3rd basemen options (Gio Urshela,
Anthony Rendon) out with injuries, on June 23, the Angels traded minor league players Coleman Crow, and Landon Marceaux to the
New York Mets for
Eduardo Escobar. On Saturday, June 24, the Angels recorded new team records for both runs and hits in a 25-1 blowout over the
Colorado Rockies. Despite outscoring the Rockies 32-12 in the series, the Angels lost the series, making the second worst run differential of a team who won a baseball series. Additionally, on June 25, the day after the 25-1 blowout, the Angels acquired
Mike Moustakas for minor league player Connor Van Scoyoc.
July On July 26, the Angels traded minor leaguers
Ky Bush and
Edgar Quero to the
Chicago White Sox for
Lucas Giolito and
Reynaldo Lopez. When asked about the trade, General Manager
Perry Minasian said: "For this team to be in this position with the injuries we’ve had, I felt like I owed it to the group to give them a better chance to win." A day after the trade, the Angels faced off against the
Detroit Tigers in a doubleheader. The Angels won both games as
Shohei Ohtani pitched a one hit complete game shut up in Game 1 and homered twice in Game 2. During the second game of a three game series with the
Toronto Blue Jays on July 29,
Taylor Ward was struck in the head by a 91mph fastball by
Alek Manoah. As the result, Taylor Ward suffered facial fractures and is put on the injury list. The following day, on July 30, the Angels traded minor leaguers Jake Madden, and Mason Albright to the
Colorado Rockies for
Randal Grichuk, and
C.J. Cron. ==Injuries==