4-AcO-DET

4-AcO-DET is orally active, and doses of 10 to 25mg are common. The free base is also active when smoked in a dose range of 5 to 20mg. Smoking 4-AcO-DET greatly speeds up the onset; peak effects are experienced within 10minutes, and are usually over within 1 hour. ==Interactions==

It is expected that 4-AcO-DET is quickly hydrolyzed into the free phenolic 4-HO-DET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking. ==Chemistry==

Analogues Analogues of 4-AcO-DET include diethyltryptamine (DET), 4-HO-DET (ethocin), ethocybin (4-PO-DET), 4-AcO-DMT (psilacetin), 4-AcO-DPT, 4-AcO-MET, and 4-AcO-MPT, among others. ==Society and culture==

Legal status Canada 4-AcO-DET is not an explicitly nor implicitly controlled substance in Canada as of 2025. Finland Listed in the "government decree on psychoactive substances banned from the consumer market". Sweden Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-AcO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-acetoxi-N,N-dietyltryptamin (4-AcO-DET), making it illegal to sell or possess. United States 4-AcO-DET is not an explicitly controlled substance in the United States. However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption. ==See also==