The club was founded in 1921 as
Associazione Sportiva Sambonifacese. In 1943 it was renamed to
Associazione Calcio Sambonifacese. In the
2007–08 season of Serie D, Sambonifacese finished 3rd in Girone C, qualifying for the promotional playoffs. As the playoff winner, the team won special promotion to Serie C2, now called Lega Pro Seconda Divisione, as one of the 5 top teams in the promotional playoffs. In the 2011–12 season, it was relegated from
Lega Pro Seconda Divisione/A to
Serie D. ==Colors and badge==