MarketButalbital/acetaminophen
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Butalbital/acetaminophen

Butalbital/acetaminophen, sold under the brand name Butapap among others, is a combination medication used to treat tension headaches and migraine headaches. It contains butalbital, a barbiturate and paracetamol (acetaminophen), an analgesic. Versions also containing caffeine are sold under the brand name Fioricet among others. It is taken by mouth. The combination is also sold with codeine.

Medical uses
Butalbital/acetaminophen is indicated for the treatment of tension headaches. Butalbital/acetaminophen/caffeine is indicated for the treatment of tension headaches. ==Side effects==
Side effects
Prolonged use can cause rebound headaches. Rarely, use of barbiturates can lead to Stevens–Johnson syndrome. ==Mechanism of action==
Mechanism of action
Butalbital has a half-life of about 35 hours. Acetaminophen has a half-life of about 1.25 to 3 hours, but may be increased by liver damage and after an overdose. Caffeine has a half-life of about 2.5 to 4.5 hours. == References ==
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