Of primary cause Treatment of the primary cause, if known, is essential. In
psychogenic cases, dealing with psychological factors is most important. Factors should be identified such as being left alone all day, being confined, and changes in the household. Correction of these causes may include increased walks, avoiding confinement, and more interaction in the home. Some veterinarians have proposed that diet can affect
compulsive behaviors in dogs. Drugs may be used until
behavior modification has had time to take effect.
Antidepressants are most commonly used, including
doxepin,
amitriptyline,
fluoxetine, and
clomipramine. If the psychological factors are not corrected, the pet will usually relapse after the drugs are discontinued.
Endorphin blockers such as
naltrexone can be used to reduce addiction to licking, or endorphin substitutes such as
hydrocodone may decrease the urge to lick.
Of lesion The lesion should also be treated. Class 4 infrared laser treatments have been used with much success, although it may take several treatments to achieve the desired outcome. Licking can be prevented by the use of
Elizabethan collars, dog leggings, battery-enhanced wraps, bandages, anti-licking ointments (which are bad tasting), and anti-lick strips (which are either bad tasting or simply provide a barrier). It is important to catch lesions early and keep the animal from licking them to then reduce inflammation and development of a habit.
Topical medications such as
corticosteroids or
DMSO may be effective if used early. Small lesions may be injected with
triamcinolone or
methylprednisolone. Oral
antibiotics are used to control infection. Surgery may be performed to remove whole lesions, but there is risk of continued self-mutilation to the area afterwards. Other potential treatments include
cryosurgery,
laser surgery,
radiation therapy, and
acupuncture. It is important to note that many dogs will lick at another leg, another area on the same leg, or someplace else, creating a new lick granuloma, if they are prevented from licking at the original one while it heals.
Success rate Overall, lick granulomas are very difficult to treat, with control only being achieved in about 65 percent of cases. Some animals will continue to lick at the area despite the use of anti-lick ointments or sprays to deter them, for instance. ==Commonly affected dog breeds==