In acute decompensated heart failure, the immediate goal is to re-establish adequate perfusion and oxygen delivery to end organs. This entails ensuring that
airway, breathing, and circulation are adequate. Management consists of propping up the head of the patient, giving oxygen to correct hypoxemia, administering morphine, diuretics like
furosemide, addition of an ACE inhibitor, use of nitrates and use of
digoxin if indicated for the heart failure and if arrhythmic.
Oxygen Supplemental oxygen may be administered if
blood levels of oxygen are low; the Heart Failure Society of America, however, has recommended that it not be used routinely.
Medication Initial therapy of acute decompensated heart failure usually includes some combination of a vasodilator such as nitroglycerin, a
loop diuretic such as
furosemide, and
non-invasive positive pressure ventilation (NIPPV). A number of different medications are required for people who are experiencing heart failure. Common types of medications that are prescribed for heart failure patients include
ACE inhibitors,
vasodilators,
beta blockers,
aspirin,
calcium channel blockers, and
cholesterol lowering medications such as
statins. Depending on the type of damage a patient has suffered and the underlying cause of the heart failure, any of these drug classes or a combination of them can be prescribed. Patients with heart pumping problems will use a different medication combination than those who are experiencing problems with the heart's ability to fill properly during
diastole. Potentially dangerous drug interactions can occur when different drugs mix together and work against each other.
Vasodilators Nitrates such as
nitroglycerin (
glyceryl trinitrate) and
isosorbide dinitrate are often used as part of the initial therapy for ADHF. A 2013 Cochrane review, compared nitrates and other pharmacological, non-pharmacological, and placebo interventions.
Diuretics Heart failure is usually associated with a volume overloaded state. Therefore, those with evidence of fluid overload should be treated initially with intravenous loop diuretics. In the absence of symptomatic low blood pressure intravenous nitroglycerin is often used in addition to diuretic therapy to improve congestive symptoms.
Others ;ACE inhibitors and ARBs The effectiveness and safety of
ACE inhibitors and
angiotensin receptor blockers (ARBs) acutely in ADHF have not been well studied, but are potentially harmful. A person should be stabilized before therapy with either of these medication classes is initiated. Individuals with poor kidney perfusion are especially at risk for kidney impairment inherent with these medications. ;Beta-blockers
Beta-blockers are stopped or decreased in people with acutely decompensated heart failure and a low blood pressure. However, continuation of beta-blockers may be appropriate if the blood pressure is adequate. ;Inotropic agents
Inotropes are indicated if low blood pressure (
SBP < 90 mmHg ) is present. The
National Institutes for Health and Care Excellence (NICE) guidelines do not recommend routinely offering inotropes in acute heart failure. The
National Institutes for Health and Care Excellence (NICE) guidelines do not recommend routinely offering opioids in acute heart failure. and has been shown to reduce the risk of death. Severe
respiratory failure requires treatment with
endotracheal intubation and
mechanical ventilation.
Ultrafiltration Ultrafiltration can be used to remove fluids in people with ADHF associated with
kidney failure. Studies have found that it decreases health care utilization at 90 days. One such method is
aquapheresis ultra-filtration A 2022 Cochrane review on the benefits, efficacy, and safety of ultrafiltration compared to diuretic therapy found that ultrafiltration probably reduces the incidence of heart-failure related hospitalisation in the long term. The
National Institutes for Health and Care Excellence (NICE) guidelines do not recommend routinely offering ultrafiltration in acute heart failure. Different procedures are available depending on the level of necessity and include
coronary artery bypass surgery,
heart valve repair or replacement, or
heart transplantation. During these procedures, devices such as heart pumps,
pacemakers, or
defibrillators might be implanted. The treatment of heart disease is rapidly changing and thus new therapies for acute heart failure treatment are being introduced to save more lives from these massive attacks.
Bypass surgery is performed by removing a vein from the arm or leg, or an artery from the chest and replacing the blocked artery in the heart. This allows the blood to flow more freely through the heart. Valve repair is where the valve that is causing heart failure is modified by removing excess valve tissues that cause them to close too tightly. In some cases,
annuloplasty is required to replace the ring around the valves. If the repair of the valve is not possible, it is replaced by an
artificial heart valve. The final step is heart replacement. When severe heart failure is present and medicines or other heart procedures are not effective, the diseased heart needs to be replaced. Another common procedure used to treat heart failure patients is an
angioplasty. Is a procedure used to improve the symptoms of
coronary artery disease (CAD), reduce the damage to the heart muscle after a
heart attack, and reduce the risk of death in some patients. A
pacemaker is a small device that's placed in the chest or abdomen to help control abnormal heart rhythms. They work by sending electric pulses to the heart to prompt it to beat at a rate that is considered to be normal and are used to treat patients with arrhythmias. They can be used to treat hearts that are classified as either a
tachycardia that beats too fast, or a
bradycardia that beats too slow. ==See also==