Insecticides A subclass of acylureas known as
benzoylureas are
insecticides. They act as
insect growth regulators by inhibiting the synthesis of
chitin resulting in weakened
cuticles and preventing
molting. Members of this class include
diflubenzuron, flufenoxuron, hexaflumuron,
lufenuron, and teflubenzuron.
Anticonvulsants and sedatives The acylurea functional group is also found in some pharmaceutical drugs such as the
anticonvulsants
phenacemide,
pheneturide,
chlorphenacemide, and
acetylpheneturide (which are phenylureides), and the
sedatives
acecarbromal,
bromisoval, and
carbromal (which are
bromoureides). Others include
apronal (apronalide), capuride, and ectylurea.
Barbiturates (a class of cyclic ureas) are structurally and mechanistically related to them. The phenylureides are also closely related to the
hydantoins, such as
phenytoin, and may be considered ring-opened analogues of them. ==Related==