ADAM22 is a member of the
ADAM (
A Disintegrin
And
Metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom
disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including
fertilization, muscle development, and
neurogenesis. This gene is highly expressed in the brain and may function as an
integrin ligand in the brain. Alternative splicing results in several transcript variants. == Interactions ==