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Adhesive capsulitis of the shoulder

Adhesive capsulitis, also known as frozen shoulder, is a condition associated with shoulder pain and stiffness. Onset is gradual over weeks to months. A common shoulder ailment, adhesive capsulitis is marked by pain at rest but especially upon movement, as well as a decrease in range of motion. The shoulder itself, however, often does not hurt significantly when touched.

Signs and symptoms
Adhesive capsulitis presents with progressively worsening shoulder pain and limited range of motion. Pain due to frozen shoulder is usually dull or aching, and may be worse at night or when lying on the affected shoulder. Any movement, especially rapid or unguarded movement, can aggravate the pain. Physical exam findings include restricted range of motion in all planes of movement (but especially in external rotation), and defecits in both active and passive range of motion. This contrasts with conditions such as shoulder impingement syndrome, or rotator cuff tendinitis, in which the active range of motion is restricted but passive range of motion is normal. Some exam maneuvers of the shoulder may be impossible due to pain. The symptoms of primary frozen shoulder have been classically described as having three stages. • Stage one: The "freezing" or painful stage, which may last from two to nine months, and in which the patient has a slow onset of pain. As the pain worsens, the shoulder loses motion. == Causes ==
Causes
The exact causes of adhesive capsulitis are incompletely understood. However, the condition can sometimes occur after a known trigger, and there are several factors associated with higher risk. Adhesive capsulitis is classified depending on whether the trigger is unknown (primary) or known (secondary). In fact, diabetic adhesive capsulitis is increasingly recognized as clinically distinct from other forms of adhesive capsulitis (based on differences in clinical outcomes, pathophysiology and gene expression). A new classification system has been proposed that separates diabetic adhesive capsulitis from other forms of the condition. Secondary Adhesive capsulitis is called secondary when it develops after a known event that directly affects shoulder mobility. Such events include shoulder injury, surgery (either on the shoulder or the chest wall), and periods of prolonged shoulder immobility. == Pathophysiology ==
Pathophysiology
Adhesive capsulitis of the shoulder involves an inflammatory process within the joint, leading to the formation of scar tissue (adhesions) and shrinking (contracture) of the space inside the shoulder joint capsule. Systemic inflammation appears to play a significant role in the development of adhesive capsulitis, and many diseases with an inflammatory component are associated with increased risk. The first and most severely restricted motion is usually external rotation, primarily due to the thickening of the coracohumeral ligament which forms the roof of the rotator cuff. In addition, the thickened coracohumeral ligament contributes to limitations in internal rotation, as a result of its connection to other rotator cuff tendons. This increased stiffness and decreased joint volume is associated with difficulty moving the arm forward and out to the side. == Diagnosis ==
Diagnosis
Adhesive capsulitis is traditionally diagnosed by history and physical exam. It is often a diagnosis of exclusion, meaning it is only diagnosed after other causes of shoulder pain and stiffness have been ruled out. On physical exam, adhesive capsulitis can be diagnosed if limits of the active range of motion are the same or similar to the limits to the passive range of motion - that is, motion stops at roughly same point whether the patient moves the arm independently or the examiner moves it passively. While the range of motion in external rotation is often the most severely limited, passive range of motion in abduction is particularly useful diagnostically: restriction below 80° is a strong indicator, and restriction below 40° is nearly 100% predictive of adhesive capsulitis. Imaging Imaging studies are not required for diagnosis, but may be used to rule out other causes of pain and are often able to confirm the presence of adhesive capsulitis. Grey-scale ultrasound is increasingly used in diagnosis of adhesive capsulitis, as it is cost-effective and available even to patients who cannot undergo an MRI. == Management ==
Management
Non-surgical management is the initial treatment of choice for frozen shoulder. Common treatments include exercise, physical therapy, oral anti-inflammatory medication, and corticosteroid injections into the joint. The effects of most treatments are primarily short-term, focusing on alleviating symptoms such as shoulder pain and reduced joint movement. Corticosteroid injections appear to provide the greatest short-term improvements in pain and range of motion, while long-term outcomes tend to be similar for most non-operative treatments. Non-surgical treatment may continue for months, with more complex treatments such as extracorporeal shock wave therapy, movement under anaesthesia, and hydrodilatation. Each of these treatments have been deemed effective but have had different benefits and drawbacks, meaning that clinicians and patients often decide together on the most appropriate treatment. Gentle movement-based approaches may be used to help maintain mobility and manage discomfort during recovery, such as Tai Chi and the Feldenkrais Method. Most people (around 90%) can see their symptoms resolve with nonsurgical management alone. If conservative measures have no effect and the condition is long-lasting, or if evidence suggests surgical intervention, there are several operative procedures that can be used. This systematic review and meta-analysis found that combining acupuncture with physical therapy may reduce pain and improve shoulder range of motion more than physical therapy alone in patients with frozen shoulders. Exercise and manual techniques are kept limited when pain is high, and gradually increased as pain subsides. Especially in the painful (freezing) stage of adhesive capsulitis, it is recommended that stretching exercises not exceed the threshold of pain and be kept short (1–5 seconds). Other non-operative interventions Nerve block at the suprascapular nerve (SSNB) is a minimally invasive procedure that can provide significant pain relief and functional improvement by directly blocking the main nerve for sensation to the shoulder (suprascapular nerve). There is some evidence that SSNB is superior to corticosteroid injections and physical therapy. Hydrodilatation has also been combined with SSNB, but seems to provide no additional benefit. Surgical evaluation of other potential problems with the shoulder, e.g., subacromial bursitis or rotator cuff tear, may be needed. Rotator cuff tears that exist alongside adhesive capsulitis can be addressed during the same surgery. Manipulation under anesthesia Performed in isolation or during capsular release surgery, manipulation under anaesthesia is a procedure that aims to directly break up adhesions in the shoulder by manually moving the arm. General anesthesia is given to prevent pain and resistance during the procedure. While manipulation under anaesthesia without capsular release surgery appears similarly effective and can be more cost-efficient, the procedure carries additional risk of fracture, dislocation, tendon rupture, and nerve injury. Post-operative management After surgery, it is recommended that rehabilitative physical therapy begin within 24–72 hours and continue 2-3 times per week for at least 6 weeks. Physical therapy is utilized to regain range of motion and prevent stiffness. Range of motion exercises, such as passive and active assisted exercises, are used first to provide mobility to the joints while preventing further stress/damage to the healing tissues. Stretching exercises are usually added later, followed by strengthening exercises. == Prognosis ==
Prognosis
Adhesive capsulitis is generally self-limiting, and has favorable long-term outcomes. Many people experience a painful "freezing" phase (2–9 months), stiff "frozen" phase (4–12 months) and "thawing" recovery phase (5–24 months), after which symptoms resolve. == Epidemiology ==
Epidemiology
Adhesive capsulitis affects between 2-5% of the general population, and every year there are approximately 2.4 new cases per 1,000 people. Women are affected disproportionately - approximately 60-70% of people who experience adhesive capsulitis are female. Both type 1 diabetes and type 2 diabetes are risk factors for the condition. == See also ==
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