In 1845, her brother Sultan Abdulmejid arranged her marriage to
Damat Mehmet Ali Pasha, who had been serving as an advisor in the imperial arsenal. Born in
Hemşin, he was the son of Hacı Ömer Agha, the chief agha of
Galata. He came to Istanbul at a very young age, where he spent his childhood in the Enderun. The preparations for the marriage began on 24 March 1845, and the marriage contract was concluded on 27 April in the apartment of the sacred relics,
Topkapı Palace. After the ceremony was performed, the trousseau was brought to the Darüssaade Ağa from where it was taken through Tophane Street to Çırağan Palace. The wedding celebrations were delayed until the next summer. The wedding took place on 7 June 1845, and lasted a whole week. On the last day of the celebrations, Adile was taken to
Neşatabad Palace located in Defterdarburnu. This palace once belonged to
Hatice Sultan, daughter of Sultan
Mustafa III. After the marriage, Mehmet Ali Pasha became commander of the fleet, and served in this position for five times, and afterwards served a short while as Grand Vizier to her brother, Sultan Abdulmejid. The couple had four children together, including one son, Sultanzade Ismail Bey, and three daughters, Hayriye Hanımsultan, Sıdıka Hanımsultan, and Aliye Hanımsultan. Mehmet Ali Pasha died in 1868 during the reign of Adile's younger half-brother, Sultan
Abdulaziz. Their only surviving daughter, Hayriye was born in 1846, and died in 1869, a year after her father. In 1861 her half-brother
Abdülaziz, with whom she was not on good terms, ascended the throne. To reconcile with him he introduced him to
Edadil Hanim, a lady whom Abdülaziz took as his consort. Adile wrote several components to celebrate their son,
Şehzade Mahmud Celaleddin. ==Religiosity==