The Agua Caliente Handicap is a defunct thoroughbred horse race that was once the premier event at Agua Caliente Racetrack in Tijuana, Baja California, Mexico, and the richest race in North America. Inaugurated in 1917 as the Coffroth Handicap, it was named in honor of James Wood Coffroth, President of the Lower California Jockey Club. It was run at the Tijuana Racetrack through 1929 after which it was hosted by the newly built Agua Caliente Racetrack.