De Sequeira first worked at
Morgan Stanley in 1994, where she completed an
internship while in business school. She joined the firm full-time in
New York City when she graduated the following year, becoming an associate in their
Investment Banking group. A few months later, she moved to the
Mergers & Acquisitions (M&A) group, where she would continue until 2007. Three months after her transfer, the company was caught by the
2008 financial crisis; while deals were scarce, De Sequeira's team was able to find contacts with potential clients. Hence, they were ready when the markets began to recover in 2009, and it was called the top firm in the capital markets in India after advising 17 deals in nine months. in addition to her Investment Banking position. She continued in both roles through December 2020. Under De Sequeira's leadership, Morgan Stanley India maintained its status as a prominent M&A advisory firm, and became the top firm in the country again in 2017. The company advised over $70 billion of deals, such as the investments by
Facebook, Inc. and
Google into
Jio; She was also a member of the
Young Presidents' Organization.
Indra Nooyi, also a Yale SOM alumna, was a friend and mentor. == Personal life ==