North of its southern terminus, SR 35 begins an ascent over
Lookout Mountain as a two-lane road. The highway heads in a northwesterly direction as it travels through the
Little River Canyon National Preserve along the county line dividing Cherokee County and
DeKalb County leading into
Fort Payne. As the highway descends Lookout Mountain, within the Fort Payne
city limits, it makes a 90-degree right turn at the foot of the mountain. Numerous trucks descending this route have suffered brake failure and wrecked at this turn as a result, causing numerous fatalities. One resident living at this turn, Joe Faulkner, erected a reinforced concrete wall to protect his property. The wall assumed the popular name, "Joe's Truck Stop." (1930) carrying the southbound lanes of SR 35 over the
Tennessee River at
Scottsboro From Fort Payne, SR 35 is routed along a four-lane divided highway as it heads towards
Rainsville. The highway is a four-lane highway from its intersection with
US 11 in Fort Payne to its intersection with
US 72 in
Scottsboro, except for a brief stretch from near its intersection with
SR 71 in
Section, to the foot of
Sand Mountain and the east bank of the
Tennessee River, where it intersects
SR 40. The
Alabama Department of Transportation plans to eventually four-lane this remaining section of the Fort Payne–Scottsboro route. The highway crosses the Tennessee River over the
Comer Bridge (southbound) and the
Bob Jones Bridge (northbound). A new bridge is under construction to replace the Comer Bridge, and was expected to open in 2012, but finally opened May 2016. In the early 1990s, a section of the highway was rerouted from a dogleg extending from Fort Payne through Pine Ridge to Rainsville along the natural slope of Sand Mountain, to the current four-lane route. The current route reaches the brow of Sand Mountain along a ramp through a manmade gap in the side of the mountain. Until 1980, the northern terminus of SR 35 was at Scottsboro, where it intersected US 72. It was extended westward along the former alignment of US 72 after the U.S. Highway was relocated to a new four-lane highway between Scottsboro and
Huntsville. Although SR 35 travels in a south by southwestward trajectory as it leaves Scottsboro, it is signed as “SR 35 north” until its terminus at a second intersection with US 72 at
Woodville in western
Jackson County. ==Major intersections==