Isley released her self-produced debut EP
The Love Art/Memoirs in 2012. Isley described her music as r&b with hip hop and jazz influences. In November 2019 she released the joint EP
Wilton with producer Jack Dine. In May 2020 Isley performed a remote concert and a studio concert June 2025 for
NPR's
Tiny Desk series. In 2022 she released
Marigold, a collaborative album with Jack Dine. Jackie B. of
Soul Bounce reviewed the project positively: "Alex Isley and Jack Dine remain as a melodious match made in heaven as they take us through a cycle from sprout to blossom to full bloom on
Marigold." She was featured on
Tank's recent single "No Limit" from his 10th album
R&B Money. Isley released the album
I Left My Heart in Ladera with
Terrace Martin in October 2023. The album, her first to chart on
Billboard, debuted at number two on Billboard's Contemporary Jazz Albums list and at number 22 on Jazz Albums. She earned her first two
Grammy Award nominations as a featured artist on "Back to Love" by
Robert Glasper at the
66th Annual Grammy Awards. The song was nominated for Best R&B Song and Best R&B Performance. In February 2025, Isley signed to the imprint Free Lunch Agency which is distributed by
Warner Records. == Personal life ==