Nacional In July 2016, Medina returned to his former club Nacional, as a manager of the youth setup. On 12 December of the following year, he was named manager of the first team in the place of
Martín Lasarte. Medina led Nacional to the Championship play-off in his first season, but lost to eventual champions
Peñarol. On 7 December 2018, he resigned.
Talleres On 6 June 2019, Medina replaced departing
Juan Pablo Vojvoda at the helm of
Talleres in the Argentine top tier. In his first season, he qualified the club to the
Copa Sudamericana, and led the side to an impressive third-place finish in the
2021 campaign; he also reached the
Final of the
2019–20 Copa Argentina, but lost on penalties to
Boca Juniors. On 23 December 2021, Medina left Talleres as his contract was due to expire.
Internacional On 27 December 2021, Medina was appointed manager of
Campeonato Brasileiro Série A side
Internacional on a one-year contract. He was sacked the following 15 April, after a 1–1 draw with Paraguayan side
Guaireña.
Vélez Sarsfield On 24 May 2022, Medina agreed to become the manager of
Vélez Sarsfield, returning to Argentina after nearly six months. He left the club on a mutual agreement the following 26 February.
Granada On 27 November 2023, Medina replaced
Paco López at the helm of
La Liga side
Granada. He was dismissed on 19 March 2024, after winning one of his 14 games in charge. ==Managerial statistics==