Charles Norris established the Office of the Chief Medical Examiner (OCME) in 1918 and set up his first offices in the Pathology Building (the 'City Morgue') of Bellevue Hospital. Gettler often had to create new tests to isolate poisons. He regularly experimented by poisoning raw liver and attempting to isolate ever-smaller amounts of poison from it. These tests often involved mashing or liquifying tissue, followed by such tests as
crystal formation,
melting and
boiling point analysis, color reactions, and
titration. In addition to this, Gettler wrote numerous papers on isolating poisons such as
benzene from human bodies. In 1933, Gettler was among the first to recognize a normal endogenous presence of
carbon monoxide in the human body and was the first to suggest the
human gut microbiome as a contributing source. Gettler often had to work for low pay, due to severe budget cuts to the toxicology office. == Teaching ==