In 2007, Grant had her first solo exhibition at the
Museum of Contemporary Art (MOCA) in Los Angeles, curated by
Alma Ruiz. A catalog from the exhibition features Grant's large-scale works on paper, an essay on Grant's work by Ruiz, and an essay that inspired Grant by the French writer and philosopher
Hélène Cixous. Grant's artworks joined a multi-artist show in
Tel Aviv in 2008, titled "From and About Place: Art from Los Angeles". Grant's work has been described as a "radical collaboration", that is, work made in collaboration with the text and work of other writers and artists, and is often participatory and ongoing. The longest exchange has been with the pioneering writer of hypertext fiction,
Michael Joyce. The paintings and sculpture based on Joyce's texts (using them as scores or scripts to interpret rather than follow) have been the subject of at least three series: the "Ladder Quartet" (shown at MOCA in 2007), the "Six Portals" (shown at Honor Fraser gallery in 2008), and "Bodies" (shown at Honor Fraser gallery in 2010). In 2008, she participated in
Edgar Arceneaux’s Watts House Project, a non-profit group that aimed to renovate houses across the Watts Towers, in Los Angeles. Each of the households who agreed to participate in the project was appointed a team of an artist and an architect to remodel their homes. The initial plan for Grant’s “Love House” was to build a large construction of her brands’ logo (LOVE) over the house. However, years passed with no major constructions taking place to any of the houses and a dispute with the IRS and the Watts House project in general, has prevented it to come to fruition. Grant resigned from the projects’ board but is still raising funds in order to complete the “Love House”. In 2013, Grant collaborated on twin series of exhibitions with Cixous, based on the latter's book
Philippines. The "Forêt Intérieure/Interior Forest” exhibition first took place at
18th Street Arts Center in Santa Monica, and at Mains d’Oeuvres in Saint-Ouen, France. Participants joined Grant in creating large-scale drawings of Cixous's novel, which touched on many themes including telepathy in Cixous and the work of
Jacques Derrida and
Sigmund Freud. Grant and Cixous spoke about their telepathic relationship in 2013 as part of a conversation from Mains d’Oeuvres to Nottingham Contemporary in 2016. 18th Street Arts Center published the “Forêt Intérieure/Interior Forest” to thank the many participants in the project, a catalog which includes photographs of both exhibitions, and essays by Cixous, Grant, curator Pilar Tompkins Rivas, Robert Nashak, and a transcription of Grant's 2013 conversation with Cixous. These works were inspired by the documentary film
Century of the Self by BBC documentarian
Adam Curtis. In 2015, Grant exhibited her work in a painting called “Antigone 3000” inspired by the Greek myth, and specifically a phrase in Sophocles's play where Antigone confronts her uncle Creon—the king—and says, “I was born to love not to hate.” Works from Antigone 3000 have been shown at the Barnsdall Art Center, when Grant won the City of Los Angeles Mid-Career Artist Award (COLA) in 2015 and most recently in 2017 at the
Los Angeles County Museum of Art (LACMA) as part of the exhibition “L.A. Exuberance: Recent Gifts by Artists.” In 2017, Grant wrote the text for "Antigone is me" with her sister, Florence Grant, which is meant to capture the ancient Greek myth Antigone in a contemporary scene. The exhibit was a community-based project installation held at
The Eastern Star Gallery at The Archer School for Girls in Los Angeles. Grant has cited
R.B. Kitaj as an influence.
Teaching Grant has worked as a professor. From 2009 to 2011, she was an adjunct professor at Art Center College of Design (Pasadena, CA). In 2010, Grant taught an MFA seminar at Cal State Northridge and from 2013 to 2014 was a mentor in the
Pacific Northwest College of Art's Distance MFA program. In 2015, Grant was an MFA program mentor at
Syracuse University, and co-taught a course with Isabelle Lutterodt at Ashesi University in Accra, Ghana.
Film In 2015, as part of a residency at the
Bemis Center for Contemporary Art in Omaha, Nebraska, Grant directed a documentary film called
Taking Lena Home. The film was about returning a stolen tombstone to rural Nebraska.
Books In 2009, Grant met actor
Keanu Reeves at a social event. This led to
Ode to Happiness, published by
Gerhard Steidl in early 2011, Grant's first collaboration with Reeves. It was Grant's first artist book and Reeves's first book as a writer. As part of the release of the book, Grant did a collaboration with artist Alia Raza for
Issue magazine that featured fashion and shadows.
X Artists' Books In 2017 Grant, alongside designer Jessica Fleischmann and
Keanu Reeves, established a small publishing company called X Artists Books, sometimes abbreviated XAB. ==Personal life==