In 1982, at the age of 12, Arquette's first acting gig was as "this little kid who's on a ride with all these women and whatnot" in the music video "
She's a Beauty" by
The Tubes. In 1986, Arquette made her big screen debut in an uncredited role as Alexis, the
androgynous friend and bandmate of sexually ambivalent teenager Max Whiteman (Evan Richards) in
Down and Out in Beverly Hills. Arquette, in the earlier years of her career, primarily performed as a female impersonator, frequently under the name "Eva Destruction". Later in her career, Arquette made public that she had begun the process leading to
sex reassignment surgery. To this end, Arquette had publicly declared that she considered her
gender to be female. At 19, Arquette played
trans sex worker Georgette in the screen adaptation of
Last Exit to Brooklyn. The majority of Arquette's film work was in low-budget or
independent films. In total, Arquette starred in more than 40 movies, including
I Think I Do, Children of the Corn V: Fields of Terror, and
Sometimes They Come Back... Again. Arquette also starred as a
crack addict opposite
Tim Roth in ''
Jumpin' at the Boneyard, as a teenage boy seeking revenge for a horrible childhood in the New Zealand-shot horror fantasy Jack Be Nimble, and as a murderous drag queen in the low budget comedy Killer Drag Queens on Dope''. Arquette also had supporting roles in
Pulp Fiction,
Threesome and
Bride of Chucky, and she played a
Boy George fanatic, George Stitzer, in the
Adam Sandler–
Drew Barrymore film
The Wedding Singer, singing "
Do You Really Want to Hurt Me" over and over. Her role as Georgina, a Boy George impersonator, in another Sandler–Barrymore film,
Blended, was a reference to that role. In 2001, Arquette returned to New Zealand to play
Roman emperor
Caligula in two episodes of
Xena: Warrior Princess. That same year, Arquette guest starred in the
Friends episode "
The One with Chandler's Dad", in which she directly interacted with her sister-in-law,
Courteney Cox. Also in the same year, she cameoed in
Son of the Beach. In September 2005,
VH1 announced Arquette as one of the celebrity house-guests on the 6th season of
The Surreal Life. On January 31, 2007, Arquette was a featured celebrity client and guest judge on the première episode of
Bravo's reality show
Top Design. Arquette also made a cameo appearance in the music video for
Robbie Williams' song "
She's Madonna". ==Personal life==