One of ten children, her siblings include Anne, wife of
Francis Lovell, 1st Viscount Lovell; Margery, who married Sir
Marmaduke Constable; Joan, a nun;
Elizabeth Fitzhugh (grandmother to Queen
Catherine Parr), who married
Sir William Parr and then
Sir Nicholas Vaux; and Richard,
6th Baron FitzHugh who married Hon. Elizabeth Burgh, daughter of
Thomas Burgh, 1st Baron Burgh; their son, George, inherited the barony of FitzHugh, but after his death in 1513 the barony fell into abeyance between Alice and her nephew
Sir Thomas Parr. This abeyance continues to the present day. Her maternal grandparents were
Richard Neville, 5th Earl of Salisbury and
Lady Alice Montague, 5th Countess of Salisbury,
suo jure, only daughter and heiress of
Thomas Montacute, 4th Earl of Salisbury and
Lady Eleanor Holland. Her paternal grandparents were William FitzHugh, 4th Baron FitzHugh and Margery Willoughby. Through her grandfather, the Earl of Salisbury, she was a niece of
Richard Neville, 16th Earl of Warwick (known in history as "Warwick, the Kingmaker"), a grandniece of
Cecily Neville, Duchess of York (mother of King
Edward IV and King
Richard III) and a great-grandniece of King
Henry IV. Through her great-grandmother,
Eleanor Holland, she was a great-great-grandniece of King
Richard II and was also related to the
York line of Kings and their successor Henry Tudor, who became King
Henry VII. == Marriage and issue ==