Whittemore was born on July 5, 1936. She originally studied pure mathematics. She obtained a bachelor's degree in 1958 from
Marymount Manhattan College, and a master's degree in 1964 from
Hunter College. Whittemore completed a Ph.D. in 1967, from the
Graduate Center of the City University of New York with a dissertation on
Frattini subgroups supervised by
Gilbert Baumslag. As a professor of mathematics at Hunter College, she became interested in epidemiology and statistics. While teaching in Hunter College's new statistics program, she reportedly taught herself statistics by reading the textbook just a few pages ahead of her students, completing all the exercises herself before assigning them to the class. She pursued a fellowship to
New York University to accomplish that shift of interests, under the mentorship of
Joseph Keller. Keller and Whittemore married and moved together to Stanford in 1978. There Whittemore became a professor in the Department of Health Research and Policy. She was chief of epidemiology there from 1997 to 2001, and later became co-chair of the department. Keller died in 2016. Whittemore died on December 2, 2025 in her home in
Palm Desert, California, at the age of 89. ==Contributions==