After studying advertising at the public University of the Basque Country (UPV), Waddington worked for three years as an advertising creative, producer, and advertising video editor at agencies including
Leo Burnett Iberia and Social Noise, also specializing as a digital storyboard artist. In 2014, Waddington took a hiatus from advertising agency work to write and direct her first narrative short film,
Disco Inferno (2015), with executive producer Yadira Ávalos. The 11-minute film received nominations at more than 60 international film festivals, including
Palm Springs International ShortFest,
Fantasia,
Sitges (Noves Visions Short award), and
Fantastic Fest. The film won Best Director at Fantastic Fest and the Silver Feature Film Project Award at the festival’s film market, leading to the development of Waddington’s debut feature
Paradise Hills. Waddington entered pre-production on her debut feature film,
Paradise Hills, in 2017 with Spanish production company Nostromo Pictures. Written by Brian DeLeeuw and
Nacho Vigalondo, the science-fiction thriller starred Emma Roberts, Awkwafina,
Eiza González, Danielle Macdonald,
Milla Jovovich, and Jeremy Irvine. The film premiered at the
Sundance Film Festival in 2019, becoming the second Spanish debut feature ever selected by the festival, and went on to screen at more than twenty international genre festivals, including Fantasia, Sitges, and Mórbido. In June 2019, it was announced that Waddington was developing her second feature film,
Scarlet, from a script co-written with Kristen SaBerre, with Waddington also serving as executive producer. The project was developed at
MGM/Orion and produced by Aggregate Entertainment. In September 2021, Waddington was announced as director of the Netflix adaptation of the Dark Horse Entertainment comic series
Dept. H, with a script by screenwriter T. S. Nowlin, known for
The Maze Runner film series and
Pacific Rim: Uprising. In October 2022, Waddington premiered her first television episode at the Sitges Film Festival as part of Amazon Prime Video Spain’s revival of
Historias para no Dormir. Her episode,
La Pesadilla, was written with established Spanish showrunner Rocío Martínez Llano and is a remake of a 1967 story by legendary horror pioneer Chicho Ibáñez Serrador. In 2023, Waddington and the Benson sisters sold an adaptation of the fantasy novel series
The Witchlands to a major U.S. studio, with Waddington attached to direct the project. Waddington is also a co-writer and director on the segment
Red Shoes for the 2026 feature-length horror anthology film
Tales from the Woods, produced by Wayward Entertainment. The anthology includes segments directed by multiple filmmakers, including Benson & Moorhead. In 2026, Waddington is attached to adapt a novel for Addictive Pictures under its genre imprint Neotext. == Social activism ==