The anime focuses on the
custody battle for Ryūnosuke and the attempts by Akiko and Mishima Heavy Industries to reclaim Nuku Nuku's body, which often involves amusingly larger-than-life battles between Nuku Nuku and military hardware produced by Mishima Heavy Industries. Two episodes also deal with a one-sided war between Nuku Nuku and another android named Eimi Yoshikawa, who suffers from an over-the-top
inferiority complex and envies Nuku Nuku's more stable design. As it stands, Eimi was made after her and seeks to transfer her programming into Nuku Nuku to ditch her own body, which Akiko calls "a piece of junk".
Characters •
Atsuko "Nuku Nuku" Natsume – The protagonist and titular character, Nuku Nuku started out as a stray cat, Ryūnosuke. While on the run with her father Kyūsaku, she stumbled upon Kyūsaku's prototype android. She acts over-protective yet childish, being easily distracted by stereotypical feline things like mice, but shows a sincere desire to evolve and grow. •
Ryūnosuke Natsume – The son of a brilliant if absent minded scientist and the over protective CEO of Japan's number one weapon's manufacturer, Ryū has the ability of squeezing in a normal life and quality time with either of his parents. He loves Nuku Nuku as a sister, but is agitated when his father brushes off her blunders as 'just being a cat' when at the same time granting her the respect and responsibilities of a human being. •
Kyūsaku Natsume – A scientist who created a prototype android with funding from his wife's company. However, with the amount of cash being dumped into the project he realized that his android would be sold off as a weapon. Having no desire to aid his wife's weapon's research he fled with his son in tow. He and his wife are not technically divorced and will still chat and bicker like any married couple when the chance arises. He created add-ons for Nuku Nuku on at least one occasion to outfit her for unique situations. •
Akiko Natsume – CEO of Japan's biggest military contractor, and an over-protective mother, Akiko aims to reclaim Ryūnosuke from her husband and capture Nuku Nuku. Despite her love of firepower, she loves Ryūnosuke and only wants to give her best for him. •
Eimi Yoshikawa – An android built in the image of the deceased granddaughter of Kyūsaku Natsume's mentor, Eimi is emotionally, mentally, and physically unstable. Built in the image of a girl around Ryū's age, Eimi's activation resulted in an explosion that killed her grandfather, leaving her legally the property of Akiko's company. She often lets her own impatience get the better things of her. •
Arisa Sono and
Kyōko Ariyoshi: Akiko's two loyal henchwomen, they spearhead the attacks on Nuku Nuku and frequently suffer the consequences. Arisa is the more violent of the two and prefers to use weapons in order to get her way, something which Kyōko tries to restrain. ==Media==