Trimble was a clerk of the Common Pleas Court in 1808. He also served as recorder of deeds in 1808. After briefly serving during the
War of 1812, Trimble served in the
Ohio House of Representatives from 1816 to 1817 and then in the
Ohio State Senate from 1818 to 1826. Trimble became Speaker of the Senate, and it was in this capacity that he became governor from January to December 1822 when Governor
Ethan Allen Brown resigned to take a seat in the
United States Senate. Trimble ran an election for a full term in
1822, but narrowly lost. He challenged
Jeremiah Morrow again in
1824, narrowing the distance between the two, but still losing. He won a landslide election in 1826, however, as a
National Republican and then won a second full term in 1828. Trimble did not seek re-election in 1830. He then retired to farming, taking little part in politics for the next quarter-century, but did consent to accepting the nomination of the
Know-Nothings for governor in
1855. Trimble came in third, losing to
Republican US Senator Salmon Chase and incumbent
Democrat William Medill. In 1860 he was a delegate to the
Constitutional Union Party convention in Baltimore. ==Death==