Alto Guadalquivir is a Spanish comarca in the province of Córdoba. It covers an area of 1,299 km², and has a population of 44,828 inhabitants. It borders the comarca of Valle de los Pedroches to the North; Campiña Este - Guadajoz to the South; Córdoba and the comarca of Valle del Guadiato to the West; and the province of Jaén to the East.